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The First Collection of Smart Smoothies

Rooted in Science. Designed for Rapid Results.
BALANCE
Matcha + Ashwagandha

GUT HEALTH

Our BALANCE Smoothie is designed to help reduce stress, promote gut health and stimulate detoxification. Pumpkin seeds, matcha and ashwagandha assist in balancing cortisol levels, while spirulina, wheatgrass and barley grass help support internal cleansing. Added prebiotics, probiotics and enzymes give this smoothie an extra boost to nourish the microbiome and eliminate bloat — once and for all.

Flavor Profile: Green Tea Ice Cream

Benefits:

Ingredients: Pumpkin Seed Protein*, Pea Protein*, Maca*, Tocotrienols*, Banana*, Psyllium Husk*, Ceremonial Matcha*, Ashwagandha*, Spirulina*, Barley Grass*, Wheatgrass*, Ginger Root*, Yacon Root*, Coconut Milk*, Enzyme Blend, Probiotic Blend, Locust Bean Gum*, Xanthan Gum, Stevia Reb-A*  *Certified Organic

ENERGIZE
Cacao + Lion’s Mane

METABOLISM

Our ENERGIZE Smoothie is designed to boost the happy chemicals in your brain. With cacao, lion’s mane and reishi, this blend contains a cocktail of nutrients that have been studied to prevent depression, reduce fatigue and improve immunity. Together these ingredients function to lift your mood and give you the energy you need to start – and finish – your day.

Flavor Profile: Chocolate Milkshake

Benefits:

Ingredients: Pumpkin Seed Protein*, Pea Protein*, Cacao*, Maca*, Tocotrienols*, Black Sesame Seeds*, Banana*, Lucuma*, Lion’s Mane*, Reishi*, Enzyme Blend, Probiotic Blend, Locust Bean Gum*, Xanthan Gum, Ceylon Cinnamon*, Yacon Root*, Stevia Reb-A*, Pink Himalayan Salt  *Certified Organic

CALM
Turmeric + Ginger

DE-STRESS

Our CALM Smoothie kicks inflammation to the curb with powerful herbs that target the cells and support immunity. We’ve added high-potency curcumin for serious results and added vitamin E in the form of tocotrienols to control and activate agents that regulate inflammation. Alongside ginger and cinnamon, these botanicals work in synergy to support cellular function.

Flavor Profile: Golden Mylk Latte

Benefits:

Ingredients: Pumpkin Seed Protein*, Pea Protein*, Maca*, Tocotrienols*, Flax Seeds*, Turmeric*, Ginger*, Ceylon Cinnamon*, Curcumin*, Enzyme Blend, Probiotic Blend, Locust Bean Gum*, Xanthan Gum, Stevia*  *Certified Organic

REJUVENATE
Maqui + Baobab

GLOWING SKIN

Our REJUVENATE Smoothie is filled with antioxidant-rich botanicals that combat oxidative stress, reduce the effects of aging, and work alongside vitamin C to stimulate healthy collagen production. Both chaga and maca contain enzymes that increase each other’s antioxidant potency, sesame seeds and tocotrienols together increase absorption of vitamin E, and sesame seeds and maca work together to balance hormones — all to leave you feeling your lightest and brightest.

Flavor Profile: Berry Sorbet

Benefits:

Ingredients: Pumpkin Seed Protein*, Pea Protein*, Maca*, Maqui Berry*, Açai*, Baobab*, Tocotrienols*, Black Sesame Seeds*, Chaga*, Enzyme Blend, Probiotic Blend, Locust Bean Gum*, Xanthan Gum, Stevia Reb-A*  *Certified Organic

ILLUMINATE
Banana + Chaga

FOCUS

Our ILLUMINATE Smoothie is specifically designed to protect acetylcholine — the neurotransmitter in the brain responsible for memory, learning, and emotional response. Lion’s mane increases the production of acetylcholine, chaga protects it from oxidative stress, and maca inhibits AcHE — an enzyme that destroys acetylcholine. Together these ingredients help keep you sharp so you can remember where you put those keys.

Flavor Profile: Banana muffin

Benefits:

Ingredients: Pumpkin Seed Protein*, Pea Protein*, Maca*, Tocotrienols* , Lucuma*, Banana*, Chaga*, Lion’s Mane*, Mesquite*, Enzyme Blend, Probiotic Blend, Locust Bean Gum*, Xanthan Gum, Ceylon Cinnamon*, Vanilla Bean*, Stevia Reb-A*  *Certified Organic

Nutrition Panel

Research-Backed Recipes For Cellular Health

Nourish Your Whole Body in One Daily Step
Box of 5
REJUVENATE
Maqui + Baobab
Antioxidants for Glowing Skin

Aging – in a nutshell – is what happens when our cells get lost or damaged. For example, the fewer skin cells we have, the thinner our skin becomes. We can’t stop the natural process of aging from happening, but we can certainly stop premature aging from getting the best of us. Premature aging happens when we are exposed to free radicals and we don’t have enough antioxidants in our bodies to balance them out. This process is referred to as oxidative stress, and leads to low energy, inflammation, and a variety of chronic diseases including cancer.

Free radicals are unstable oxygen molecules – molecules that have lost an electron and are trying to become stable again. Electrons like to be in pairs, so they steal electrons from others. This eventually causes other neighboring cells to oxidize.

Hairspray contains free radicals, microwaves make molecules in your food unstable resulting in free radicals, and even exercising creates free radicals as a byproduct of your cells making energy. The body naturally generates antioxidants to fix the issue, but in today’s world we are exposed to so many free radicals that our bodies simply can’t keep up. If you live in the middle of a busy city, just going outside and breathing pollution creates free radicals. Helping your body create its own antioxidants and consuming plenty of antioxidants through your diet are important mechanisms to help balance the system.

The REJUVENATE smoothie has been specifically designed with plenty of powerful antioxidants like maqui berries, baobab, acai berries and chaga to help balance your system, combat oxidative stress, and slow the process of premature aging.

 

ILLUMINATE
Banana + Chaga
Mushrooms to Boost Your Brain

The gut communicates with the brain via the vagus nerve. This nerve runs from to the brain to the abdomen, linking to every organ in between. The vagus nerve is extremely fragile and is highly affected by nutrition and any imbalance in the gut biome.

One of the ways the brain connects to the gut – like a walkie-talkie – is through the hippocampus. When the vagus nerve is activated it leads to the release of the neurotransmitter acetycholine. Acetylcholine is associated with learning, memory, mood and behavior.

The vagus nerve also comes into play when your sympathetic nervous system shifts into a “fight or flight” response. It pours the stress hormones cortisol and adrenaline into your body. And when it’s time to loosen back up, the vagus nerve releases acetylcholine.

Our ILLUMINATE smoothie has been designed to strengthen the gut-brain connection. We’ve formulated it with ingredients that help stimulate and protect acytocholine including lion’s mane, chaga, and maca.

 

BALANCE
Matcha + Ashwagandha
Adaptogens to Improve Gut Health

The gut is responsible for dictating so much of what we do and how we feel on a daily basis. It has recently been labeled “the second brain,” showing just how pivotal a role it plays in our health and longevity. Most of our serotonin (the neurotransmitter associated with happiness and wellbeing) is produced in the gut by the gut microbiomes. These microbes are responsible for synthesizing some of the vitamins in the body, helping with digestion of food, and maintaining immune health. Without them, we simply wouldn’t exist.

Diet and stress are major factors in gut health and microbiome balance. In fact, stress alone can cause severe illnesses like diabetes, hormone imbalance, thyroid dysfunction and mental health issues. Recent studies have shown that an increase in stress can bring populations of gut bacteria down, and bacteria populations can directly influence stress levels.

The BALANCE smoothie is filled with adaptogenic herbs like ashwagandha that help alleviate stress. Other ingredients including enzymes, probiotics, ginger, psyllium husk and yacon root help support the digestive system, which inherently reduces stress.

 

CALM
Turmeric + Ginger
Roots to Combat Inflammation

The mitochondria – your energy factories – are located inside of your cells. There are approximately 2,500 mitochondria per cell. When chronic inflammation occurs, the effects include reduced glucose availability and a reduction in energy. As a result of injured cells, not much can get in and not much can get out of the cell, negatively affecting the way the mitochondria work to produce energy. Chronic fatigue, weight gain, hormone imbalance and poor mood are all symptoms of inflammation.

Glucose is the preferred energy source of the brain and most of the organs in your body, including the thyroid, and liver.  Without properly functioning cells, the brain does not get the appropriate amount of ATP it needs. This leaves you to forget your keys, lose your phone, etc.

The CALM smoothie contains specific properties that help the body combat inflammation, and thus maintain the ability to use glucose to produce energy. The combination of curcumin and ginger has been used for centuries in Ayurveda and Chinese Medicine to reduce inflammation. CALM contains an array of anti-inflammatory ingredients like curcumin, turmeric, ginger, and enzymes to help reduce inflammation and ease digestion.

 

 

ENERGIZE
Cacao + Lion’s Mane
Polyphenols to Support Cell Metabolism and Energy

We come full circle here with energy and cell metabolism. Keeping your cells healthy is directly linked to longevity. In this context, longevity means living a long, high-quality life free of diseases, premature aging, chronic stress and fatigue. Energy is something that we all want, because without it we wouldn’t be able to do the things we love.

Sure, you can go and get a cup of coffee for quick energy, but that will just drain the liver of its stored glucose and perpetuate the cycle of adrenaline and glucose until you hit a wall.

The ENERGIZE smoothie was designed to work in synergy with CALM, REJUVENATE and BALANCE to support cell metabolism and healthy energy. Cacao has high amounts of minerals, polyphenols and other vital nutrients. Combined with lion’s mane and reishi, they support cognitive health and improve focus, while the cacao boosts your energy.

Exploring the Therapeutic Benefits of
TUSOL Ingredients

A Much Deeper Look

 

 

REJUVENATE

Maqui + Baobab

Maqui Berry 

Study funded by National Commission for Scientific and Technological Research (CONICYT, Chile),

Maqui berry is the richest known natural source of delphinidins. An in vitro assay of this purified molecule showed an increase in the generation of nitrogen oxide (NO) in endothelial cells, decreased platelet adhesion, and anti-inflammatory effects. Additionally, it has been reported that delphinidins can counteract aging of the skin and inhibit osteoporosis.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722795/#B116-foods-08-00289 

The antioxidant and anti-inflammatory effects of water extracts of maqui berry were tested in a mouse dermatitis model showing an increase of interferon-gamma (IFN-γ) levels and a decrease of interleukin-4 (IL-4), suggesting its potential use for atopic dermatitis treatment.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722795/#B116-foods-08-00289 

 

Chaga Mushroom 

University Tokyo, Japan

We showed that the continuous intake of the (Chaga) I. obliquus extract can potentially suppress cancer development through the maintenance of the body temperature. In addition, middle-aged mice drinking the (Chaga) I. obliquus extract exhibited body weight loss. Our findings suggest that the aqueous extract of (Chaga) I. obliquus could be used as a natural product for cancer suppression and general health care.

Key Findings:

The extract of I. obliquus caused significant tumor suppressive effects in both models. Thus, in tumor-bearing mice, 60% tumor reduction was observed, while in metastatic mice, the number of nodules decreased by 25% compared to the control group. Moreover, I. obliquus extract-treated mice demonstrated the increase in tumor agglomeration and inhibition of vascularization. Interestingly, I. obliquus intake decreased body weight in middle-aged mice and increased body temperature in response to light-dark switching in mature adult mice. Furthermore, I. obliquus prevented temperature drop in mice after tumor implantation

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946216/

Department of Medical Nutrition, Kyunghee University, South Korea

Chaga mushroom treatment affords cellular protection against endogenous DNA damage produced by H2O2 (Hydrogen peroxide). Chaga mushroom extract inhibits oxidative DNA damage in human lymphocytes.

https://www.ncbi.nlm.nih.gov/pubmed/15630179

 

CALM

Turmeric + Ginger 

Curcumin

University of Southern California study on amyloid plaque and curcumin

Due to various effects of curcumin, such as decreased Beta-amyloid plaques, delayed degradation of neurons, metal-chelation, anti-inflammatory, antioxidant and decreased microglia formation, the overall memory in patients with AD has improved. 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781139/

https://www.sciencedirect.com/science/article/abs/pii/S0300483X09005848

Published in Brain Research in 2006

Curcumin alleviates stress-induced decreases in Brain Derived Neutropic Factor and pCREB/CREB were also blocked by chronic curcumin administration. These results provide compelling evidence that the behavioral effects of curcumin in chronically stressed animals, and by extension humans, may be related to their modulating effects on the HPA axis and neurotrophin factor expressions

https://www.semanticscholar.org/paper/Curcumin-reverses-the-effects-of-chronic-stress-on-Xu-Ku/b26fd0a78f0ac8ebe6d084f83c4f93f9192f3f34

Ginger

Published in Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition.

The effectiveness of ginger in preventing or suppressing cancer growth has been examined in a variety of cancer types, including lymphoma, hepatoma, colorectal cancer, breast cancer, skin cancer, liver cancer, and bladder cancer. The mechanisms proposed to explain the anticancer activities of ginger and its components include antioxidant activity and the ability to induce apoptosis, decrease proliferation, cause cell-cycle arrest, and suppress activator protein 1 (AP-1) and NF-κB/COX-2 signaling pathways (Figure 7.3).

https://www.ncbi.nlm.nih.gov/books/NBK92775/

 

Maca

Palacki Univeristy, Czech Republic

Maca increased significantly the activity of SOD (superoxide dismutase) in the liver, the GPX (glutathione peroxidase) in the blood, and the level of GSH (glutathione) in the liver.

https://www.ncbi.nlm.nih.gov/pubmed/17333395

 

BALANCE

Matcha + Ashwagandha 

Wheatgrass

Published on Institute of Food Science and Technology

Wheatgrass powder (WP) showed higher radical scavenging capacity, ash and chlorophyll content and lower protein content as compared to pulse powder (PP). Wheatgrass (WJP) juice powder had significantly higher K and Mg content as compared to pulse juice powder (PJP). Powders with relatively higher K and Mg content had higher radical scavenging capacity and chlorophyll content.

 

Barley Grass

These results support that barley grass may be one of the best functional foods for preventive chronic diseases and the best raw material of modern diet structure in promoting the development of large health industry and further reveal that GABA, flavonoids, SOD, K-Ca, vitamins, and tryptophan mechanism of barley grass have preventive and therapeutic role for chronic diseases. This paper can be used as a scientific evidence for developing functional foods and novel drugs for barley grass for preventive chronic diseases.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904770/

Barley Grass is very effective in the treatment of ulcerative colitis, pancreatitis, and disorders of the gastrointestinal tract. A germinated barley foodstuff is helpful to reduce ulcerative colitis and improves symptoms by promoting the probiotics growth. Selenium-enriched barley grass has significant ameliorative effect on ethanol-induced gastric ulcer in mice

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904770/

Depression not only is one of the most widely associated mental disorders in the world, but also has been associated with the risk to develop cancer, dementia, obesity, diabetes, blood pressure, atherosclerosis, epilepsy, and stroke. There is an important role for GABAergic, glutamatergic, and cholinergic receptors in the pathomechanism of depression. The reduce epilepsy and preventive dementia as well as antidepressant of the young green barley leaf are regulated by inhibiting the hippocampus levels increased of nerve growth factor. The vitamins and minerals in BG can prevent the stress-related psychiatric disorders of depression.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904770/

 

Psyllium Husk

Immunobiology Research Program and Department of Bacteriology and Immunology, Faculty of Medicine, University of Helsinki,

Psyllium is a widely used treatment for constipation. It traps water in the intestine increasing stool water, easing defaecation and altering the colonic environment. We aimed to assess the impact of psyllium on faecal microbiota, whose key role in gut physiology is being increasingly recognised. We performed two randomised, placebo-controlled, double-blinded trials comparing 7 days of psyllium with a placebo (maltodextrin) in 8 healthy volunteers and 16 constipated patients respectively. We measured the patients’ gastrointestnal (GI) transit, faecal water content, short-chain fatty acid (SCFA) and the stool microbiota composition. While psyllium supplement had a small but significant effect on the microbial composition of healthy adults (increasing Veillonella and decreasing Subdoligranulum), in constipated subjects there were greater effects on the microbial composition (increased Lachnospira, Faecalibacterium, Phascolarctobacterium, Veillonella and Sutterella and decreased uncultured Coriobacteria and Christensenella) and alterations in the levels of acetate and propionate. We found several taxa to be associated with altered GI transit, SCFAs and faecal water content in these patients. Significant increases in three genera known to produce butyrate, Lachnospira, Roseburia and Faecalibacterium, correlated with increased faecal water. In summary, psyllium supplementation increased stool water and this was associated with significant changes in microbiota, most marked in constipated patients.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358997/

The physical effects of fiber in the small intestine drive metabolic health effects (e.g., cholesterol lowering, improved glycemic control), and efficacy is a function of the viscosity of gelforming fibers (e.g., psyllium, β‐glucan). In the large intestine, fiber can provide a laxative effect if (a) it resists fermentation to remain intact throughout the large intestine, and (b) it increases percentage of water content to soften/bulk stool (e.g., wheat bran and psyllium).

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413815/

 

Ashwagandha

Yale School of Public Health, New Haven, CT

Results: Sixty-two abstracts were screened; five human trials met inclusion criteria. Three studies compared several dosage levels of WS extract with placebos using versions of the Hamilton Anxiety Scale, with two demonstrating significant benefit of WS versus placebo, and the third demonstrating beneficial effects that approached but did not achieve significance (p=0.05). A fourth study compared naturopathic care with WS versus psychotherapy by using Beck Anxiety Inventory (BAI) scores as an outcome; BAI scores decreased by 56.5% in the WS group and decreased 30.5% for psychotherapy (p<0.0001). A fifth study measured changes in Perceived Stress Scale (PSS) scores in WS group versus placebo; there was a 44.0% reduction in PSS scores in the WS group and a 5.5% reduction in the placebo group (p<0.0001). All studies exhibited unclear or high risk of bias, and heterogenous design and reporting prevented the possibility of meta-analysis.

Conclusions: All five studies concluded that WS intervention resulted in greater score improvements (significantly in most cases) than placebo in outcomes on anxiety or stress scales. Current evidence should be received with caution because of an assortment of study methods and cases of potential bias.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270108/

 

ENERGIZE

Cacao + Lion’s Mane 

Lion’s Mane 

University of Malaya, Kuala Lumpur, Malaysia.

Neurotrophic factors are important in promoting the growth and differentiation of neurons. Nerve growth factor (NGF) is essential for the maintenance of the basal forebrain cholinergic system. Hericenones and erinacines isolated from the medicinal mushroom Hericium erinaceus can induce NGF synthesis in nerve cells. In this study, we evaluated the synergistic interaction between H. erinaceus aqueous extract and exogenous NGF on the neurite outgrowth stimulation of neuroblastoma-glioma cell NG108-15. The neuroprotective effect of the mushroom extract toward oxidative stress was also studied. Aqueous extract of H. erinaceus was shown to be non-cytotoxic to human lung fibroblast MRC-5 and NG108-15 cells. The combination of 10 ng/mL NGF with 1 μg/mL mushroom extract yielded the highest percentage increase of 60.6% neurite outgrowth. The extract contained neuroactive compounds that induced the secretion of extracellular NGF in NG108-15 cells, thereby promoting neurite outgrowth activity. However, the H. erinaceus extract failed to protect NG108-15 cells subjected to oxidative stress when applied in pre-treatment and co-treatment modes. In conclusion, the aqueous extract of H. erinaceus contained neuroactive compounds which induced NGF-synthesis and promoted neurite outgrowth in NG108-15 cells. The extract also enhanced the neurite outgrowth stimulation activity of NGF when applied in combination. The aqueous preparation of H. erinaceus had neurotrophic but not neuroprotective activities.

https://www.ncbi.nlm.nih.gov/pubmed/24266378

 

Reishi

Department of Neurology, Shengjing Hospital, China Medical University, Shenyang, China

Supported by the Natural Science Foundation 

In conclusion, a variety of Ganoderma lucidum extracts have definite anti-aging properties and they exert their anti-aging effects mainly through anti-oxidation, immunomodulation and anti-neurodegeneration. G. lucidum has been viewed as an elixir since Chinese ancient times.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758346/

 

ILLUMINATE

Banana + Chaga 

Probiotics

Dundee University Gut Group, Division of Pathology and Neuroscience, Ninewells Hospital and Medical School, Dundee, UK

Three prebiotics, oligofructose, galacto-oligosaccharides and lactulose, clearly alter the balance of the large bowel microbiota by increasing bifidobacteria and Lactobacillus numbers. These carbohydrates are fermented and give rise to short-chain fatty acid and intestinal gas; however, effects on bowel habit are relatively small. Randomized-controlled trials of their effect in a clinical context are few, although animal studies show anti-inflammatory effects in inflammatory bowel disease, while calcium absorption is increased.

https://www.ncbi.nlm.nih.gov/pubmed/19459727

 

Chaga Mushroom

State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau, China

Chaga mushroom is another promising candidate in the field of medicinal mushrooms. The major constituents are betulinic acid derivatives and melano-glucan complexes, and chaga have traditionally been boiled to make a tea, which is drunk to treat a range of conditions, including cancers, viral and bacterial infections, and gastro-intestinal disorders [23,24]. Inonotus obliquus belongs to higher basidiomycetes of chaga medicinal mushrooms. Inonotus obliquus presented protective effects against the oxidative stress in the liver induced by tert-butyl hydroperoxide in primary-cultured rat hepatocytes. The above said property may be due to its ability to scavenge the free radicals and thereby it inhibits the leakage of liver marker enzymes as a result of liver damage [25]. The high total phenolic contents may be the reason for its strong antioxidant activity. Like several other mushrooms, I. obliquus also possesses anticancer activity. The ergosterol peroxide from I. obliquus exhibits anti-cancer activity by down-regulation of the β-catenin pathway in colorectal cancer and it shows that it down-regulated β-catenin signaling, which exerted anti-proliferative and pro-apoptotic activities in colorectal cancer (CRC) cells. This proves that I. obliquus can be developed as promising medicine to treat colon cancer [26]. With context to this; another study shows that ethanolic extract of Innotus obliquus induces G1 cell cycle arrest in HT-29 human colon cancer cells [27]. The biological activity of the Inonotus obliquus is mainly due to the presence of several polysaccharides, the polysaccharides of Inonotus obliquus mainly constitutes the following sugars: rhamnose, arabinose, xylose, mannose, glucose, and galactose. An interesting study finds that Inonotus obliquus polysaccharide (IOP) contains polysaccharide content of 98.6%, and Man, Rha, Glu, Gal, Xyl, and Ara in a ratio of 9.8:13.6:29.1:20.5:21.6:5.4 as monosaccharide. The study reveals that IOP induce changes in the gut microbiota and increased the Bacteroidetes at the phylum level, and brings the changes towards a healthy bacterial profile. The experiment was carried with three different doses of IOP 0.1, 0.2, and 0.4 g/kg/day. The result of the study states that the predominant phylum was Bacteroidetes, normal control (NC) shows 65.05%, 47.47% in model control (MC) group. The composition of Bacteroidetes was increased about 4.55%, 9.56%, 17.48%, and 20.81% in IOP-L, IOP-M, IOP-H, and Qingyilidan granule treated (PC) groups, respectively. The PC group (Qingyilidan granule) is the standard compared with the three different doses of IOP [28].

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618583/

Department of Neurosurgery, The Affiliated Hospital of Beihua University, Jilin, China.

The I. obliquus extract can inhibit the proliferation of tumor cells. This inhibition function is closely related to the downregulation of Bcl-2 and the upregulation of caspase-3.

https://www.ncbi.nlm.nih.gov/pubmed/24940902

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